Ali Hassanpour
Islamic Azad University, Iran
Title: Evaluation of serum levels of vitamin C, vitamin E, selenium and the activity of glutathione peroxidase enzyme in the horses with strangles
Biography
Biography: Ali Hassanpour
Abstract
This study was conducted on horses with strangles for evaluation serum concentration of Vitamin C (Vit C), Vitamin E (Vit E), Selenium (Sel) and Glutathione Peroxidase (GPx) in the horses with strangles. 60 horses confirmed on the bases of clinical and laboratory signs of strangles. Blood samples tacked from jugular vein and separated serum. Sampling performed from 52 healthy horses with similar ages, feed and condition, too. Serum concentrations of Vit E, Vit C, Se and serum’s activity of GPx, enzyme measured in the samples. Mean serum levels of selenium, vitamin E, vitamin C and serum glutathione peroxidase activity in horses with strangles were reduced and except vitamin C this reduction were significant. Patient's hemoglobin level was significantly increased. Evaluate the correlation between serum selenium and serum glutathione peroxidase activity, vitamin E and hemoglobin were found in horses with strangles showed that there is a positive correlation between serum selenium and those antioxidants and with increasing serum's selenium, those serum antioxidants increased, too. In patients this antioxidant serum marker in all three was significant (r: 0.945, r: 0.561 and r: 0.893). In healthy horses correlation between selenium with glutathione peroxidase and hemoglobin was significant but with vitamin E was non-significant. In conclusion, in horses with strangles selenium, glutathione peroxidase and vitamin E reduced and supply of these antioxidants in the treatment and control of the disease is important.
