Ahmed Gaffer Hegazi
National Research Centre, Egypt
Title: Cytokines pattern of rats infected with Toxoplasma gundii and supplemented with Capparis spinosa honey
Biography
Biography: Ahmed Gaffer Hegazi
Abstract
Objectives: This study was conducted to investigate the Cytokines pattern of rats infected with Toxoplasma Gundii and supplemented with Capparis Spinosa honey (Saudi Arabia) for a period of 28 days.
Methods: Immunoglobulin M, immunoglobulin G, and cytokines were detected by using enzyme-linked immunosorbent assays (ELISAs). In addition, the mortality and the morbidity rates were assessed.
Results: Oral administration of Capparis spinosa honey as a natural food additive was experimentally shown to increase the antibody titer; furthermore, compared with the rats in the control group, the levels of the sera cytokines (IFN-γ, IL-1 and IL-6) were consistently higher at day 7 post-infection in the infected rats treated with oral supplements of Capparis spinosa honey.
Conclusion: Orally administered supplements of Capparis spinosa honey increased both the antibody titer and the cytokines (IFN-γ, IL-1 and IL-6) levels in rats infected with Toxoplasma gundii.